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Search Results for " insulin protease "

Targets

2

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T2626 SBC-115076 SBC115076 Others , Serine/threonin kinase
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
T35802 ML-345
Insulin-degrading enzyme (IDE) is a thiol-sensitive zinc-metallopeptidase that acts as the major insulin-degrading protease in vivo, mediating the termination of insulin signaling. [1] In addition to regulating insulin a...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00851 IDE Protein, Human, Recombinant (His) Human HEK293 Cells
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a r...
TMPH-02342 Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc) Hypoderma lineatum E. coli
This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-|-Try-16 and 22-Arg-|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-P...
TMPY-01893 Serpin A12 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin,...
TMPY-01551 Serpin B8 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesi...
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